Muscle load and constriction of the rabbit ear artery.

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Biphasic vasoconstriction of the rabbit ear artery.

Sympathetic nerve stimulation and intralummal norepinephrine infusion for more than 15 seconds produced a biphasic response in the isolated rabbit ear artery perfused with RREBS solution. This response consisted of an initial rapid constriction (phase A), which was followed by partial relaxation, and a final slowly developing constriction (phase B), which lasted for the duration of nerve stimul...

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Electro- and pharmacomechanical coupling in the smooth muscle cells of the rabbit ear artery

A contraction of the rabbit ear artery can be induced by depolarizing the cells with a K-rich solution if Ca is present. 10(-9)-10(-6) M noradrenaline and 10(-8)-10(-7) M histamine cause a contraction of this tissue without modifying the membrane potential. If the histamine concentration exceeds 10(-7) M some depolarization of the membrane also occurs. Both noradrenaline and histamine also indu...

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Electro- and Pharmacomechanical Coupling in the Smooth Muscle Cells of the Rabbit Ear Artery

A ~ S T R A C T A contraction of the rabbit ear ar tery can be induced by depola r iz ing the cells with a K-rich solution if Ca is present . 10 -9-10 -8 M no rad rena l ine and 10 -s10 -7 M his tamine cause a contraction of this tissue without modify ing the m e m brane potent ial . If the his tamine concent ra t ion exceeds 10 -~ M some depolar iza t ion of the membrane also occurs. Both nora...

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Electro- and Pharmacomechanical Coupling in the Smooth Muscle Cells of the Rabbit Ear Artery

A ~ S T R A C T A contraction of the rabbit ear ar tery can be induced by depola r iz ing the cells with a K-rich solution if Ca is present . 10 -9-10 -8 M no rad rena l ine and 10 -s10 -7 M his tamine cause a contraction of this tissue without modify ing the m e m brane potent ial . If the his tamine concent ra t ion exceeds 10 -~ M some depolar iza t ion of the membrane also occurs. Both nora...

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Electro- and Pharmacomechanical Coupling in the Smooth Muscle Cells of the Rabbit Ear Artery

A ~ S T R A C T A contraction of the rabbit ear ar tery can be induced by depola r iz ing the cells with a K-rich solution if Ca is present . 10 -9-10 -8 M no rad rena l ine and 10 -s10 -7 M his tamine cause a contraction of this tissue without modify ing the m e m brane potent ial . If the his tamine concent ra t ion exceeds 10 -~ M some depolar iza t ion of the membrane also occurs. Both nora...

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ژورنال

عنوان ژورنال: The Journal of Physiology

سال: 1975

ISSN: 0022-3751

DOI: 10.1113/jphysiol.1975.sp010987